Are their medications checked against their genes?
Every patient’s metabolism is different, and many are on multiple medications.
Precivo flags high-risk claims, assists in the ordering of genetic testing, and gets a clinician-reviewed clinical package to the treating doctor to minimize the risk.
A common risk. Rarely caught in time.
leading cause of death in the US. Adverse drug events, at an estimated 250,000 deaths a year, now surpass stroke and respiratory disease, and it’s getting worse: ADR mortality rose 63% from 1999 to 2020.
American Society of Pharmacovigilance, 2025 · CDC mortality-data analysis, 1999–2020
emergency department visits and 500,000 hospitalizations a year from adverse drug events, likely an undercount since these reactions are widely under-reported.
added to the cost of a hospital stay when an adverse drug event occurs during that admission, compared with a stay without one, a range still reflected in current literature.
AHRQ / HCUP Statistical Brief, 2018 (2010–2014 data) · Durand et al., Health Economics Review, 2024
increase in U.S. A patient taking multiple medications at the same time, commonly defined as five or more. prevalence between 1999 and 2018 (8.2% to 17.1%). A December 2025 analysis confirms medication counts keep climbing.
Research shows the risk can be mitigated.
of people, across independent studies in Taiwan, Switzerland, and U.S. pediatric oncology, carry at least one clinically actionable How a person's genes affect their response to specific drugs. variant.
Frontiers in Genetics, 2022 · Clinical and Translational Science, 2024 · JNCI, 2025
in monthly per-member savings from a PGx-enriched medication management program for a Medicare Advantage population.
reduction in hospitalizations for high-risk members in a state-run virtual pharmacist program that checks a patient’s medication list against itself for drug-drug interactions.
These existing tools solve part of the problem.
The result still has to be interpreted
A raw genetic result still has to be checked against the specific drug. Precivo’s reconciliation engine runs that check, and an internal clinician reviews the finding before it reaches the treating doctor.
Point-of-care alerts get overridden
Clinicians override drug-interaction alerts 49% to 96% of the time across published studies. A flashing mid-visit alert isn’t the same as a reviewed package already in the doctor’s inbox.
Nothing triggers the check on its own
Today, that check only happens if a clinician orders it, or after something has already gone wrong. Precivo is triggered by the claim itself, catching risk before it becomes an adverse event.
Let’s talk about fit.
Precivo is in active development. If you’re an MCO, payer, or provider network, let’s talk about what an early partnership could look like.
Precivo is in development. This site describes the intended workflow and access model. The current build is a prototype using synthetic data, and the decentralized storage layer described above is not yet live. Clinical validation and payer integrations remain in progress.